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Partners:
Core competence in endocytosis, molecular cell biology, biochemistry, HC assays and image analysis (cooperation with Prof. Y. Kalaidzidis, MPI-CBG), genomic siRNA and compound libraries HTS for drug development (cooperation with HT-TDS).
Liver cell biology and TGF-β signalling, liver disease mechanisms and target identification with pathobiochemical relevance.
Drug discovery cell culture tools, development of multi-well based mini-bioreactor for polarized hepatocytes, drug biotransformation and development with pharmaceutical companies.
Miniaturized and automated solutions for the life sciences, drug discovery services, offering combinatorial libraries and lead optimization, biological assay development and data generation in HTS. Drs. Martin Daffertshofer (Vice President Drug Discovery) and Carsten Claussen (CEO) will work and represent ET in the current project.
Cognition Network Technology for image analysis, integration of human models of perception into software, analysis complex biological systems applied to biotechnology.The Definiens research department (Prof. Gerd Binnig, CTO), Dr. Günter Schmidt (Senior Scientist, IP Management), Dr. Maria Athelogou (Senior Scientist, scientific project management), will work and represent Definiens AG in the current project.
Computational approaches to study the structure, dynamics, interactions and reactions of bio-macromolecules for in-depth simulation or scaled to protein families and whole genomes.
Expertise in threading and modeling software, phylogenetic analysis of protein families.
Analysis of spatio-temporal pattern formation in biological systems at the molecular and cellular scale (Deutsch and Dormann, 2004).
Proteinstrukturtheorie
Self-assembling systems in theoretical and computational context, molecular information processing systems. |